So Close to My Heart by audrarose -- (Jared/Jensen, NC-17, 15,900 words) -- Jared is a heart surgeon, Jensen is a single dad. There's love and complications and family. No fic has made me feel like this one in a really long time. I love it SO MUCH. You've probably already found this one, but just in case you haven't....go read!
There's thunder in my heart by estei -- (Jared/Jensen, NC-17) -- Their relationship isn't exactly what Jensen thinks it is. It's more. The writing here is gorgeous and emotional and visual.
Wasted on the Young by causeways and memphis86 -- (Jared/Jensen, NC-17, 15,000 words) -- Age-regression fic! Which I have been WANTING! Jared is regressed to age five and Jensen has to deal with it. Among his trials? Applesauce, water slides, nap-time and his attraction to adult-Jared. This fic is HILARIOUS and awesome and funny and sweet and every other good word you can think of.
darker shade of black by sardonicsmiley -- (Sam/Dean, R) -- WARNING: VIOLENCE. This is AU Sam and Dean as serial killers trying to escape from prison. THIS IS NOT A HAPPY FIC. It is disturbing and gross and violent and sick. All that is made even worse by the fact that I have emotional attachments to the main characters. It's also incredibly well written and detailed and vivid. I haven't been able to stop thinking about it since I read it. You won't be able to either.